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Resource scarcity combined with both an increasing supply of innovations and rising demand for health care is leading to growing pressure on decision-making processes in health systems. This raises questions regarding the ways in which limited health care resources may be allocated to produce optimal outcomes. This book presents experiences concerning the tension between the normative basis and the process of priority setting, examines specific criteria for prioritization, explains methodological approaches and discusses economic issues. The contributing authors are leading scientists, thinkers and practitioners from different academic disciplines and countries who come together to consider the legal, philosophical, and economic aspects of priority setting in medicine and to discuss the framework within which decisions on prioritization are made.