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Nutrient canals are clearly visible in intra-oral periapical radiographs (IOPAR) which are routinely used in diagnosing and evaluating diseases of teeth and jaw. If established facts are available about the nutrient canals, it would be easy for any clinician to interpret the nutrient canals which would become a diagnostic marker for systemic diseases. The principle rationale for the use of radiographically observable nutrient canals is due to its association with various systemic diseases and an increase in the number and frequency of these canals with the duration of the disease. Thus, the role of the dentist in recognizing subtle differences such as appearance of nutrient canals in diagnostic radiographs, which can be used as a marker of various systemic diseases like hypertension cannot be overlooked.