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Breast cancer patients receiving chemotherapy often §present with lowered serum albumin concentrations, §which results in treatment delays. The delay in §chemotherapy treatment has financial, medical and §emotional consequences on the patients, as well as §patient s families. The objective of this study was §to determine the effect of an optimal energy §increased protein dietary treatment on serum albumin §concentrations, anthropometrical status and quality §of life of second line breast cancer patients §receiving chemotherapy. A clinical trial, with only §female breast cancer patients was conducted. §Baseline and three-weekly visits involved §determining serum albumin concentrations, several §anthropometrical assessments, and the completion of §a quality of life questionnaire for a period of 3 §months. The information and results should help §clinicians in their daily decision making in the §nutritional management of breast cancer patients, §and be useful for professionals in the field of §cancer and nutrition.